Effect of Levodopa on Blood Pressure and Baroreflex Function in Parkinson’s Disease (P5-3.003)

Timi Earl; Amani Jridi; Perla Thulin; Meghan Zorn; Kathleen McKee; Kristin Mitrovich; Paolo Moretti; Jumana Alshaikh; Panagiotis Kassavetis; Melissa Cortez; Guillaume Lamotte

doi:10.1212/wnl.0000000000204657

April 9, 2024Neurology

Effect of Levodopa on Blood Pressure and Baroreflex Function in Parkinson’s Disease (P5-3.003)

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Key Points

Levodopa effects on blood pressure and baroreflex function are examined across Parkinson disease cohorts with and without neurogenic orthostatic hypotension.
Assessment compares vascular responses and baroreflex function between Parkinson disease individuals presenting with neurogenic orthostatic hypotension and controls.
Findings may clarify how levodopa alters blood pressure regulation, highlighting cardiovascular impacts in Parkinson disease patients with orthostatic hypotension.

Implication

Analysis uncovers levodopa influences on blood pressure and baroreflex function in Parkinson disease cohorts, indicating implications for treating neurogenic orthostatic hypotension.

Abstract

We investigated the effect of levodopa on blood pressure and baroreflex function in individuals with Parkinson disease (PD) with (PD+OH) and without neurogenic OH (PD−OH).

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Cite This Study

Earl et al. (2024) studied this question.

synapsesocial.com/papers/68e6fdb8b6db643587678096 https://doi.org/10.1212/wnl.0000000000204657

View Full Paper

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Effect of Levodopa on Blood Pressure and Baroreflex Function in Parkinson’s Disease (P5-3.003)

Key Points

Implication

Abstract

Discussion

Cite This Study

Effect of Levodopa on Blood Pressure and Baroreflex Function in Parkinson’s Disease (P5-3.003)

Key Points

Implication

Abstract

Discussion

Cite This Study

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