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April 3, 2024Oral Oncology ReportsOpen Access

Salivary 8-hydroxydeoxyguanosine (8-OHdG) – A potential DNA damage biomarker in tobacco chewers with and without periodontitis: A case control study

Arulmozhi Priyadharsini Nataraj Rajkumar Krishnan Amritha James A. Ramesh Kumar R. Ashwini

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Abstract

• The present study revealed substantial differences in the concentration of salivary 8-OHdG between healthy controls, Tobacco chewers with periodontitis and tobacco chewers without periodontitis indicating that salivary 8-OHdG is a potential biomarker in the diagnosis of DNA damage in tobacco chewers. • Salivary 8-OHdG can also be used as an early biomarker to indicate onset of carcinogenesis.

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Cite This Study

Arulmozhi et al. (2024) studied this question.

synapsesocial.com/papers/68e709f8b6db643587683a10 https://doi.org/10.1016/j.oor.2024.100313

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