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March 30, 2024Journal of Clinical PathologyOpen Access

Morphology combined withHER2D-DISH ploidy analysis to diagnose partial hydatidiform mole: an evaluation audit using molecular genotyping

Caroline Joyce Geoffrey J. Maher Susan Dineen Nirosha Suraweera Tommie V. McCarthy John Coulter Keelin O’Donoghue Michael J. Seckl Brendan Fitzgerald

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Abstract

A hydatidiform mole (HM) is classified as complete (CHM) or partial (PHM) based on its morphology and genomic composition. Ancillary techniques are often required to confirm a morphologically suspected PHM diagnosis. This study sought to evaluate the clinical accuracy of PHM diagnosis using morphological assessment supported by

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Cite This Study

Joyce et al. (2024) studied this question.

synapsesocial.com/papers/68e719e8b6db64358769386e https://doi.org/10.1136/jcp-2023-209269

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Enhancing Clinicopathological Diagnosis of Hydatidiform Mole Through the Combined Application of Histomorphologic Analysis, Immunohistochemical Analysis of p57 Expression, and Short Tandem Repeat Typing Method2024
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3Association between Histomorphological Types of Hydatidiform Mole and the Expression of Ki67 Immunohistochemical Marker as well as β-hCG Level Status2024
4Novel scoring system provides high separation of diploidy and triploidy to aid partial hydatidiform mole diagnosis: an adaption of<i>HER2</i>D-DISH for ploidy analysis2024 · 4 citations
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