Integrative multi-omics identifies regulatory and exhausted T cell types and novel immunotherapy targets in CLL lymph nodes

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Integrative multi-omics reveals a regulatory and exhausted T-cell landscape in CLL and identifies galectin-9 as an immunotherapy target2025 · 23 citations
2. 2IL‑10 limits CLL progression by reprogramming T cell exhaustion and myeloid suppression2025
3. 3Functional differences between CLL‐ and ALL‐derived CAR T cells in a 3D tumor microenvironment highlight CXCR4 and IL‐10 as potential modulatory targets2025 · 2 citations
4. 4Integrative Analysis of Multi-Omics Data to Identify Deregulated Molecular Pathways and Druggable Targets in Chronic Lymphocytic Leukemia2024 · 3 citations
5. 5Spatial transcriptomic analysis of chronic lymphocytic leukemia lymph nodes reveals tumor microenvironment evolution during disease progression2025