Melatonin: A helpful adjuvant in treating oral potentially malignant disorders and oral squamous cell carcinoma?

• Melatonin has important physiological functions that may have clinical applications in preventing and treating oral cancer. • In chronic tobacco consumers, elderly etc., the administration of melatonin, in local or systemic form, might be indicated with the goal to protect their mouth against oral malignancy. • Melatonin can be used as an adjunct in management of oral cancer patients to retard the growth of tumor and enhance the immunity of patients.