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March 22, 2024Cancer Research

Abstract 4388: Tumor-associated RhoA mutants interact with effectors in both GDP- and GTP-bound states

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Authors

YLYuan LinCincinnati Children's Hospital Medical CenterTRTheresa A. RamelotRensselaer Polytechnic InstituteSSSimge SenyuzKoç University

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Lin et al. (2024) studied this question.

synapsesocial.com/papers/68e72ce5b6db6435876a6ceahttps://doi.org/10.1158/1538-7445.am2024-4388
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Tumor-derived RHOA mutants interact with effectors in the GDP-bound state2024 · 9 citations
  2. 2Pathogenic single nucleotide polymorphisms in RhoA gene: Insights into structural and functional impacts on RhoA-PLD1 interaction through molecular dynamics simulation2024
  3. 3Divergent Morphologies and Common Signaling Features of Active and Inactive Oncogenic RHOA Mutants in Yeast2025
  4. 4The role of RhoA in diffuse large B-cell lymphoma2025
  5. 5Comprehensive molecular characterization of Rho GTPases and their regulators across human cancers.2025 · 2 citations