Key points are not available for this paper at this time.
Comprehensive Summary A new, selective Ru(II)‐catalyzed alkynylation reaction of isoquinolones, quinazolones and phthalazinones with readily available bromoalkynes has been developed. This reaction enables the selective construction of a new C(sp 2 )‐C(sp) bond through C—H activation and C—Br functionalization, and offers an effective and selective route to synthesizing highly valuable alkynylated isoquinolone, quinazolone and phthalazinone derivatives with a wide substrate scope and high selectivity.
Luo et al. (2024) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: