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March 8, 2024Journal of the American Heart AssociationOpen Access

Characterizing the Causal Pathway From Childhood Adiposity to Right Heart Physiology and Pulmonary Circulation Using Lifecourse Mendelian Randomization

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Authors

GLGenevieve M LeydenUniversity of BristolHUHelena UrquijoUniversity of BristolAHAlun D. HughesGeneral Cardiology

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Leyden et al. (2024) studied this question.

synapsesocial.com/papers/68e751c1b6db6435876ca08chttps://doi.org/10.1161/jaha.123.030453
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Also Consider

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  1. 1A lifecourse mendelian randomization study highlights the long-term influence of childhood body size on later life heart structure2022 · 29 citations
  2. 2Impact of adiposity on cardiac structure in adult life: the childhood determinants of adult health (CDAH) study2014 · 23 citations
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  4. 4Childhood adiposity affects cardiac structure, function and disease risk in later life: evidence of a causal association2025
  5. 5Long-Term Excessive Body Weight and Adult Left Ventricular Hypertrophy Are Linked Through Later-Life Body Size and Blood Pressure2017 · 36 citations