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March 4, 2024Open Access

Figure S4 from Improving Intracellular Delivery of an Antibody–Drug Conjugate Targeting Carcinoembryonic Antigen Increases Efficacy at Clinically Relevant Doses In Vivo

Ian Nessler Baron Rubahamya Anna Kopp Scott Hofsess Thomas M. Cardillo Nalini Sathyanarayan Jennifer Donnell Serengulam V. Govindan Greg M. Thurber

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Abstract

HiSep XAb-SN-38. HPLC detection at 360 nm, SN-38 absorbance region, with 98.7% associated with the peak corresponding to the antibody. Peak at 8.123 mm is due to unremoved SN-38.

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Cite This Study

Nessler et al. (2024) studied this question.

synapsesocial.com/papers/68e75dd0b6db6435876d4c20 https://doi.org/10.1158/1535-7163.25338061

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1Figure S3 from Improving Intracellular Delivery of an Antibody–Drug Conjugate Targeting Carcinoembryonic Antigen Increases Efficacy at Clinically Relevant Doses <i>In Vivo</i>2024
2Figure S2 from Improving Intracellular Delivery of an Antibody–Drug Conjugate Targeting Carcinoembryonic Antigen Increases Efficacy at Clinically Relevant Doses <i>In Vivo</i>2024
3Figure S1 from Improving Intracellular Delivery of an Antibody–Drug Conjugate Targeting Carcinoembryonic Antigen Increases Efficacy at Clinically Relevant Doses <i>In Vivo</i>2024
4Figure S6 from Improving Intracellular Delivery of an Antibody–Drug Conjugate Targeting Carcinoembryonic Antigen Increases Efficacy at Clinically Relevant Doses <i>In Vivo</i>2024
5Figure S5 from Improving Intracellular Delivery of an Antibody–Drug Conjugate Targeting Carcinoembryonic Antigen Increases Efficacy at Clinically Relevant Doses <i>In Vivo</i>2024