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March 4, 2024Open Access

Figure S7 from Improving Intracellular Delivery of an Antibody–Drug Conjugate Targeting Carcinoembryonic Antigen Increases Efficacy at Clinically Relevant Doses In Vivo

Ian Nessler Baron Rubahamya Anna Kopp Scott Hofsess Thomas M. Cardillo Nalini Sathyanarayan Jennifer Donnell Serengulam V. Govindan Greg M. Thurber

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Abstract

Spider plots of tumor growth. Nude mice bearing LS174T xenografts were injected with 4 doses of 10 mg/kg (marked with arrows on day 0, 4, 8, and 12) of either LG, XAb-SN-38, or vehicle. Individual growth curves for all mice are shown.

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Nessler et al. (2024) studied this question.

synapsesocial.com/papers/68e75dd0b6db6435876d4c2d https://doi.org/10.1158/1535-7163.25338052

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1Figure S6 from Improving Intracellular Delivery of an Antibody–Drug Conjugate Targeting Carcinoembryonic Antigen Increases Efficacy at Clinically Relevant Doses <i>In Vivo</i>2024
2Figure S2 from Improving Intracellular Delivery of an Antibody–Drug Conjugate Targeting Carcinoembryonic Antigen Increases Efficacy at Clinically Relevant Doses <i>In Vivo</i>2024
3Figure S3 from Improving Intracellular Delivery of an Antibody–Drug Conjugate Targeting Carcinoembryonic Antigen Increases Efficacy at Clinically Relevant Doses <i>In Vivo</i>2024
4Figure S4 from Improving Intracellular Delivery of an Antibody–Drug Conjugate Targeting Carcinoembryonic Antigen Increases Efficacy at Clinically Relevant Doses <i>In Vivo</i>2024
5Figure S5 from Improving Intracellular Delivery of an Antibody–Drug Conjugate Targeting Carcinoembryonic Antigen Increases Efficacy at Clinically Relevant Doses <i>In Vivo</i>2024