Abstract 1880 Traditional herbal product, Shankhapushpi, as a neuroprotective agent

Shankhapushpi (SP), scientifically known as Convolvulus pluricaulis, is a herb extensively utilized in Ayurvedic medicine, reputed for its cognitive-enhancing properties. This plant has gained attention for its potential therapeutic applications, particularly in cognitive and neural health. The herb contains various bioactive compounds, including flavonoids, glycosides, and alkaloids, which are believed to contribute to its nootropic effects. These compounds are thought to facilitate neurotransmission, enhance synaptic plasticity, and improve memory formation and retrieval processes. In addition to its memory-enhancing properties, SP exhibits significant neuroprotective effects. It is postulated that the herb's neuroprotective action is mediated through its antioxidant properties. SP scavenges free radicals, thereby reducing oxidative stress, a known contributor to neuronal damage and a common pathway in the pathogenesis of neurodegenerative diseases. Preliminary studies have shown neuroprotective properties of SP by a free radical scavenging mechanism. Prolonged cell survival and inhibition to apoptotic pathways and reduction in beta amyloid formation are being investigated. The potential use of SP in managing Alzheimer's disease and other neurodegenerative conditions is an area of growing interest. SP's bioactive compounds might interact with these pathological processes, offering a novel approach to managing or even preventing the onset of such conditions. Bhisé Global Understanding Research/Creative Work Grant.