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Hyaluronidase is one of the most popular therapeutic agents in modern dermatology and cosmetology. It is used both by injection and in the form of topical therapy in order to treat various types of scars (hypertrophic, keloid, post-acne, post-burn scars), complications after the injection of fillers based on hyaluronic acid, various diseases accompanied by tissue fibrosis. With the advent of an innovative immobilized form of hyaluronidase for topical use, the possibilities of its use have expanded both in the form of monotherapy and in combined protocols with various methods of physiotherapy. The article provides an overview of the research on the effectiveness and safety of topical hyaluronidase, which is part of Imoferase® cream. The article is of interest to a wide range of specialists (cosmetologists, dermatovenerologists, plastic surgeons, physiotherapists).
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Круглова et al. (2024) studied this question.
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