February 22, 2024CancersOpen Access

Evaluation of the Prognostic Value of Pretherapeutic Magnetic Resonance Imaging in Predicting Soft Tissue Sarcoma Radiation Response: A Retrospective Study from a Large Institutional Sarcoma Imaging Database

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Authors

GVGuillaume VoginCentre Hospitalier de Luxembourg MLM Lepage JSJulia SalleronInstitut de Cancérologie de Lorraine

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Implication

Retrospective study demonstrates pretherapeutic MRI metrics predict radiation response in soft tissue sarcoma, suggesting utility for non-invasive histologic assessment.

Key Points

Pretherapeutic apparent diffusion coefficient values positively correlate with post-treatment tumor necrosis ratios in limb soft tissue sarcoma.
Apparent diffusion coefficients exceeding 161 × 10−3 mm2/s demonstrated 95% sensitivity for identifying tumors with extensive necrosis.
Assessment of 29 institutional database cases demonstrates perfusion magnetic resonance imaging may enable non-invasive response prediction.

Cite This Study

Vogin et al. (2024) studied this question.

synapsesocial.com/papers/68e780ceb6db6435876f4054 https://doi.org/10.3390/cancers16050878

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Implication

Retrospective study demonstrates pretherapeutic MRI metrics predict radiation response in soft tissue sarcoma, suggesting utility for non-invasive histologic assessment.

Evaluation of the Prognostic Value of Pretherapeutic Magnetic Resonance Imaging in Predicting Soft Tissue Sarcoma Radiation Response: A Retrospective Study from a Large Institutional Sarcoma Imaging Database

Discussion

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Implication

Key Points

Cite This Study

Evaluation of the Prognostic Value of Pretherapeutic Magnetic Resonance Imaging in Predicting Soft Tissue Sarcoma Radiation Response: A Retrospective Study from a Large Institutional Sarcoma Imaging Database

Discussion

Member takes

Implication

Key Points

Cite This Study

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