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February 16, 2024Planta Medica

Chemical Constituents from Agave applanata and Its Antihyperglycemic, Anti-inflammatory, and Antimicrobial Activities Associated with Its Tissue Repair Capability

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Authors

AAA. Berenice Aguilar‐GuadarramaMDMónica Aideé Díaz-RománMOMaribel Osorio-García

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Overview

Preclinical evaluation reveals antihyperglycemic, antimicrobial, and wound healing activities of Agave applanata leaf extracts, highlighting its potential for managing diabetic foot ulcers.

Key Points

  • Agave applanata leaf extracts demonstrate significant antihyperglycemic, anti-inflammatory, and antimicrobial activities against common diabetic foot ulcer pathogens.
  • Spectroscopic and chromatographic fractionation identified active saponins including hecogenin alongside in vivo assays of glucose tolerance and wound healing in mice.
  • These results highlight the potential of Agave applanata in promoting accelerated tissue repair; mouse model, further preclinical and clinical validation is necessary.

Cite This Study

Aguilar‐Guadarrama et al. (2024) studied this question.

synapsesocial.com/papers/68e78e33b6db6435876ffaabhttps://doi.org/10.1055/a-2270-5527
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Also Consider

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  1. 1Modulation of Inflammatory Stress Responses by Agave potatorum Promotes Wound Healing in Diabetic Mice2026
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  3. 3Investigating the antibacterial and anti-biofilm activity of agave syrup as a traditional wound remedy2025
  4. 4Anti-diabetic potential of Artemisia monosperma Delile extract related to anti-inflammatory, antioxidant, and wound-healing properties2026
  5. 5Bioactive Metabolites from Aerial Parts of Plantago indica L.: Structural Elucidation and Integrated In Vitro/In Vivo Assessment of Anti-Inflammatory and Wound-Healing Efficacy2026 · 1 citations