Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
May 8, 2026Scientific ReportsOpen Access

Anti-diabetic potential of Artemisia monosperma Delile extract related to anti-inflammatory, antioxidant, and wound-healing properties

View Full Paper
Ask AI
Bookmark
Share

Authors

HAHanaa B. AtyaMMMohamed S. MadyONOla Nosseir

Discussion

Loading...

Member takes

Overview

Randomized trial evaluates anti-diabetic, anti-inflammatory, and antioxidant effects of Artemisia monosperma extract, suggesting therapeutic benefits.

Key Points

  • The central aim is to investigate the phenolic profile and evaluate the antioxidant, anti-inflammatory, and antihyperglycemic properties of Artemisia monosperma extract.
  • Characterized phenolic compounds by HPLC-HRMS.
  • Tested antihyperglycemic activity using the Sucrose Loading Model in a Type 2 diabetes model.
  • Measured anti-inflammatory effects in LPS-stimulated RAW264.7 cells and evaluated wound healing in BJ cells.
  • DAME reduced blood glucose levels by approximately 26% in a Type 2 diabetes model using 300 mg%, comparable to diamicron.
  • In LPS-stimulated RAW264.7 cells, TNF-α and CRP gene expressions were reduced by 66% and 82%, respectively.
  • Achieved approximately 79% wound closure in BJ cells compared to 58% in controls.

Cite This Study

Atya et al. (2026) studied this question.

synapsesocial.com/papers/69fd7eb0bfa21ec5bbf06f8bhttps://doi.org/10.1038/s41598-026-50561-8
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Neuroprotective effects of Artemisia monosperma against LPS-induced neuroinflammation via TLR4 modulation and myeloperoxidase inhibition: metabolomic and molecular insights2025 · 1 citations
  2. 2Molecular docking of polyphenols and screening of antioxidant and anticancer activity of Artemisia monosperma leaf extracts in human cancer cells.2026
  3. 3Phytochemical Profiling and In Vitro/In Silico Evaluation of α‐Glucosidase Inhibition, Antimicrobial and Antioxidant Activities in <i>Retama monosperma</i> Decoctions2025
  4. 4In Vitro evaluation of the antioxidant and hypoglycemic activities of leaves extracts from Ambrosia arborescens, Buddleja incana, Aloysia citrodora, and Prunus serotina2025
  5. 5IN SILICO AND PHARMACOLOGICAL EVALUATION OF ANTIDIABETIC AND ANTIOXIDANT POTENTIAL OF SECONDARY METABOLITES FROM AEGLE MARMELOS2026