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February 12, 2024Journal of AsthmaOpen Access

Activation of Notch1-GATA3 pathway in asthma bronchial epithelial cells induced by acute PM2.5 exposure and the potential protective role of microRNA-139-5p

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Authors

JHJunjun HuangYHYan HuYWYunxia Wang

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Huang et al. (2024) studied this question.

synapsesocial.com/papers/68e79844b6db643587708b60https://doi.org/10.1080/02770903.2024.2316711
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Expression of GATA family of transcription factors in T-cells, monocytes and bronchial biopsies2001 · 80 citations
  2. 2PM2.5 downregulates MicroRNA-139-5p and induces EMT in Bronchiolar Epithelium Cells by targeting Notch12020 · 28 citations
  3. 3Inhibition of Allergic Inflammation in a Murine Model of Asthma by Expression of a Dominant-Negative Mutant of GATA-31999 · 330 citations
  4. 4Th17/Treg dysregulation in allergic asthmatic children is associated with elevated notch expression2017 · 41 citations
  5. 5Study on the mechanism of PM2.5 affecting Th1/Th2 immune imbalance through the notch signaling pathway in asthmatic mice2023 · 12 citations