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October 9, 2025Frontiers in MedicineOpen Access

Increased risk of deep vein thrombosis, pulmonary embolism, and all-cause mortality in chronic venous disorder: a large-scale retrospective cohort study

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Authors

EMEva Lotta ModereggerSDSören DrägerSPSophie L Preuß

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Overview

Retrospective cohort study shows higher mortality and thromboembolic risks in chronic venous disorder patients, indicating risk management needs.

Key Points

  • An increased risk of deep vein thrombosis was observed, indicating a significant health concern for chronic venous disorder patients.
  • Among 463,313 patients, pulmonary embolism risk increased alongside chronic venous disorder severity, pointing to critical health implications.
  • Propensity-score matching analysis indicates procedural interventions can reduce deep vein thrombosis and pulmonary embolism risks in chronic venous disorder patients.
  • CVD patients demonstrated elevated mortality risks, emphasizing essential clinical considerations for health management strategies.

Cite This Study

Moderegger et al. (2025) studied this question.

synapsesocial.com/papers/68e79cf2ed88661f66c2e125https://doi.org/10.3389/fmed.2025.1683970
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Chronic venous disease is associated with an increased risk of cardiovascular disease and mortality: evidence from a systematic review and meta-analysis totalling 13 studies and 6.4 million people2026
  2. 2THE CARDIOVASCULAR IMPACT OF CHRONIC VENOUS DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS2025
  3. 3Atherosclerosis and Its Impact on the Outcomes of Patients with Deep Venous Thrombosis2022 · 5 citations
  4. 4Association Between Asymptomatic Proximal Deep Vein Thrombosis and Mortality in Acutely Ill Medical Patients2021 · 43 citations
  5. 5Trends in the Epidemiology of Deep Vein Thrombosis and Pulmonary Embolism in Patients Undergoing Surgery2024 · 2 citations