Why the study?
Atherosclerosis and PE substantially affect cardiovascular mortality, but the impact of atherosclerosis on outcomes in DVT patients and differences by PE status needed investigation.
Does symptomatic atherosclerosis worsen outcomes (mortality and hospitalizations) in patients with deep venous thrombosis?
Population
509 DVT patients under oral anticoagulation
Comparison
With vs without symptomatic atherosclerosis (and with vs without PE)
Design
Cohort study
Follow-up
2 years
Authors
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May identify higher-risk DVT patients for monitoring; hypothesis-generating and should not yet change practice.
Does symptomatic atherosclerosis worsen outcomes (mortality and hospitalizations) in patients with deep venous thrombosis?
Symptomatic atherosclerosis is associated with significantly increased mortality and hospitalizations in patients with deep venous thrombosis on oral anticoagulation.
Keller et al. (2022) studied this question.
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