February 9, 2024PLoS ONEOpen Access

Urinary fatty acid biomarkers for prostate cancer detection

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Authors

ELElizabeth Noriega LandaThe University of Texas at El Paso GQGeorge E. QuayeChildren's Mercy Hospital XSXiaogang SuThe University of Texas at El Paso

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Implication

Diagnostic evaluation reveals urinary fatty acid models identify prostate cancer with higher accuracy than standard PSA testing, suggesting a route to reduce unnecessary biopsies.

Key Points

Urinary fatty acid profiling identifies prostate cancer non-invasively, demonstrating greater diagnostic accuracy than prostate specific antigen screening.
Stir bar sorptive extraction coupled with gas chromatography mass spectrometry models yielded an AUC of 0.71, exceeding the 0.51 AUC of standard PSA tests.
Supports urinary fatty acids as a reliable non-invasive biomarker panel for prostate cancer diagnosis, helping prevent unwarranted prostate tissue biopsies.

Cite This Study

Landa et al. (2024) studied this question.

synapsesocial.com/papers/68e7a2cdb6db64358770b9e4 https://doi.org/10.1371/journal.pone.0297615

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Implication

Diagnostic evaluation reveals urinary fatty acid models identify prostate cancer with higher accuracy than standard PSA testing, suggesting a route to reduce unnecessary biopsies.

Urinary fatty acid biomarkers for prostate cancer detection

Discussion

Member takes

Implication

Key Points

Cite This Study

Urinary fatty acid biomarkers for prostate cancer detection

Discussion

Member takes

Implication

Key Points

Cite This Study

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