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October 9, 2025Reproduction and FertilityOpen Access

Cytokine supplementation influences bovine embryo transcriptome during the preimplantation period

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Authors

KMKerry S. McDonaldRPRandall S. PratherMOM. S. Ortega

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Overview

Analysis shows FLI supplementation alters gene expression in bovine embryos, suggesting enhanced viability.

Key Points

  • FLI supplementation improved the transcriptomic profile of bovine embryos during preimplantation development.
  • At the morula stage, 580 genes were upregulated in embryos treated with FLI, indicating enhanced development.
  • Gene ontology analysis revealed significant changes in MAPK and TGF-beta signaling pathways due to FLI.
  • The findings suggest that FLI can improve embryo quality and resilience, aiding livestock reproductive biotechnologies.

Cite This Study

McDonald et al. (2025) studied this question.

synapsesocial.com/papers/68e7f0af2d7e30942762caedhttps://doi.org/10.1530/raf-25-0011
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