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October 9, 2025Circulation Research

Abstract Wed164: Aging, Alzheimer's, and Stroke: A 25-Year Longitudinal Analysis of U.S. Mortality Trends

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Authors

MMMohammad Hamza Bin Abdul MalikMAMuhammad Faizan AliHAHusnain Ahmad

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Overview

Longitudinal analysis shows declining stroke mortality in Alzheimer's patients by sex and racial disparities.

Key Points

  • Stroke-related deaths in Alzheimer's patients decreased from 1999 to 2023, signaling positive trends in mortality.
  • The age-adjusted mortality rate for stroke in Alzheimer's patients fell notably from 19.4 to 10.5 over the 25-year span.
  • Women had higher mortality rates than men, but men exhibited a steeper decline in stroke-related mortality rates.
  • Significant racial disparities remain, with non-Hispanic Blacks experiencing the highest mortality rates in this demographic.

Cite This Study

Malik et al. (2025) studied this question.

synapsesocial.com/papers/68e80eb363e2e2f707877df2https://doi.org/10.1161/res.137.suppl_1.wed164
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Aging, Alzheimer's disease, and stroke: A 25-year longitudinal analysis of U.S. mortality trends.2025 · 2 citations
  2. 2Abstract TP008: Trends and Disparities in Alzheimer Disease and Stroke-Related Deaths Among Older Adults in the United States: A CDC WONDER Analysis (1999-2023)2026
  3. 3Abstract TP111: Comparative Mortality Patterns of Stroke versus Alzheimer’s Disease: A 25-Year U.S. Analysis (1999–2023)2026
  4. 4Abstract WP138: Trends In Stroke-Related Mortality Among Patients With Atherosclerosis Aged 25 Or Older In The US From 1999-2023: A 24-year CDC WONDER Database Analysis2026
  5. 5Abstract WP103: Trends and Disparities in Non-Ischemic Heart Disease and Stroke associated mortality Among Older Adults in the United States: A CDC WONDER Analysis (1999-2023)2026