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October 10, 2025International Journal of BioprintingOpen Access

Dual-controlled-release dual-antibiotic-loaded bone scaffolds: Development and in vivo/in vitro study

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Authors

PZPeng ZhaoLSLu SiHHHuan He

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Overview

In vivo and in vitro study demonstrates effective antibiotic delivery in bone scaffolds, suggesting potential for improved healing.

Key Points

  • The dual-release scaffold effectively inhibited Staphylococcus aureus infections, enhancing bone healing.
  • In vitro tests showed that the scaffold supported osteoblast differentiation and mineralization.
  • The RM-PLGA/bFGF scaffold was developed using a double emulsion method for sustained antibiotic delivery.
  • Results indicate potential for the scaffold to achieve infection control while promoting bone tissue regeneration.

Cite This Study

Zhao et al. (2025) studied this question.

synapsesocial.com/papers/68e8ed7aa1d181ff1b94814ahttps://doi.org/10.36922/ijb025330325
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