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October 12, 2025International Journal of Molecular SciencesOpen Access

Cellular Immunity in Obesity: Pathophysiological Insights and the Impact of Bariatric Surgery

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Authors

TRTania Rivera-CarranzaAGAngélica León-Téllez GirónRGRaquel Gónzalez-Vázquez

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Overview

Narrative review explores cellular immunity and inflammation in obesity, highlighting bariatric surgery's effects.

Key Points

  • Obesity promotes chronic inflammation, contributing to chronic degenerative diseases.
  • Significant immunometabolic changes occur in obese individuals compared to those of normal weight.
  • Bariatric surgery alters immune cell composition, which may reduce obesity-related inflammation.
  • Understanding lymphocyte subpopulations can enhance therapeutic approaches for obesity-related conditions.

Cite This Study

Rivera-Carranza et al. (2025) studied this question.

synapsesocial.com/papers/68ebc91af2c3e4d8d926e44ehttps://doi.org/10.3390/ijms26209867
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Interplay between the Adaptive Immune System and Insulin Resistance in Weight Loss Induced by Bariatric Surgery2019 · 61 citations
  2. 2Obesity and Inflammation: Lessons From Bariatric Surgery2008 · 62 citations
  3. 3Bariatric Surgery Induces Alterations in the Immune Profile of Peripheral Blood T Cells2024 · 3 citations
  4. 4Distinct B cell profiles characterise healthy weight and obesity pre- and post-bariatric surgery2023 · 17 citations
  5. 5OBESITY AS A CHRONIC LOW-GRADE INFLAMMATORY DISEASE - PATHOPHYSIOLOGICAL MECHANISMS AND CLINICAL IMPLICATIONS. A REVIEW OF THE LITERATURE2026