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October 17, 2025Stroke and Vascular NeurologyOpen Access

Clinical features, treatment and long-term outcomes of hemorrhagic moyamoya disease in children: an extensive follow-up study

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Authors

CCCheng ChenGGGan GaoDLDesheng Li

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Overview

Retrospective analysis reveals high rebleeding rate in pediatric moyamoya disease, indicating early intervention with EDAS may improve outcomes.

Key Points

  • Pediatric hemorrhagic moyamoya disease has a high rebleeding rate, especially in the second decade of life.
  • Analysis of 1103 patient-years revealed 96 hemorrhagic events with significant predictors identified.
  • Early intervention with EDAS significantly reduces both rebleeding and postoperative complication rates in affected children.
  • Clinical management focusing on early EDAS can improve prognosis and minimize risks in pediatric moyamoya disease.

Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/68f199bfde32064e504dcc07https://doi.org/10.1136/svn-2025-004515
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Natural Course and Clinical Outcomes of Patients With Hemorrhagic Moyamoya Disease2026
  2. 2Hemorrhage in Adult Moyamoya Disease With Intracranial Aneurysms: A Long-Term Observational Study on the Roles of Moyamoya Vessels and Admission Glasgow Coma Scales2026
  3. 3Pediatric Hemorrhagic Moyamoya Disease2026 · 2 citations
  4. 4EXPRESS: Encephaloduroarteriosynangiosis Effectively Reduces Rebleeding Risk in Adults with Hemorrhagic Moyamoya Disease: A Long-Term Ambidirectional Cohort Study2026
  5. 5Long‐Term Hemorrhagic Morbidity for Children With Moyamoya Treated With Revascularization Surgery in a Single Center Retrospective Cohort2024