Assessment of Serum Creatine Kinase (CK) and Lactate Dehydrogenase (LDH) Levels in Patients with Thyroid Disorders: A Hospital-Based Study from Bihar

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Discussion

Observational study compared serum CK and LDH in thyroid disorders, revealing significant differences indicating metabolic changes.

Serum creatine kinase and lactate dehydrogenase levels increase significantly in hypothyroid patients compared to controls.
Hypothyroid patients showed elevated CK at 246.8 IU/L and LDH at 384.5 IU/L, unlike controls which had CK at 109.2 IU/L.
Thyroid hormones strongly correlated with serum CK and LDH levels, particularly TSH, indicating muscle involvement.
Routine testing of CK and LDH in thyroid patients may help monitor disease progression and treatment response.

Raju et al. (2025) studied this question.

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