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October 18, 2025ERJ Open ResearchOpen Access

Effect of short-term supplemental oxygen therapy on six-minute walk distance in highlanders at risk for pulmonary hypertension: a randomized, crossover trial

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Randomized crossover trial found supplemental oxygen therapy did not improve six-minute walk distance in highlanders, but reduced dyspnea.

Supplemental oxygen therapy did not enhance six-minute walk distance compared to ambient air in highlanders.
The mean six-minute walk distance was 457 meters with oxygen therapy versus 475 meters without, showing no significant improvement.
In a randomized open-label crossover trial, 47 highlanders at risk for pulmonary hypertension were evaluated for exercise performance.
This suggests that low-dose oxygen therapy requires further investigation to clarify its effects on cardiovascular stress.

Hertig et al. (2025) studied this question.

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October 18, 2025ERJ Open ResearchOpen Access

View Full Paper

Ask AI

Bookmark

Authors

Randomized crossover trial found supplemental oxygen therapy did not improve six-minute walk distance in highlanders, but reduced dyspnea.

Supplemental oxygen therapy did not enhance six-minute walk distance compared to ambient air in highlanders.
The mean six-minute walk distance was 457 meters with oxygen therapy versus 475 meters without, showing no significant improvement.
In a randomized open-label crossover trial, 47 highlanders at risk for pulmonary hypertension were evaluated for exercise performance.
This suggests that low-dose oxygen therapy requires further investigation to clarify its effects on cardiovascular stress.

Hertig et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark