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October 21, 2025Frontiers in Cardiovascular MedicineOpen Access

The kinetics of CA125 levels as a prognostic marker for in-hospital mortality in patients with acute heart failure: a pilot study

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Authors

HDHai Nguyen Ngoc DangTLThang Viet LuongTDThang Doan

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Overview

Pilot study shows elevated CA125 levels correlate with in-hospital mortality in acute heart failure patients, suggesting its prognostic potential.

Key Points

  • CA125 levels were significantly higher in acute heart failure patients, indicating a strong link to in-hospital mortality.
  • An increase in CA125 after 7 days was associated with a hazard ratio of 37.50 for higher in-hospital mortality.
  • This prospective cohort study involved 80 participants across three groups: acute heart failure, chronic heart failure, and controls.
  • The results suggest a need for larger studies to validate CA125's role as a prognostic marker in heart failure management.

Cite This Study

Dang et al. (2025) studied this question.

synapsesocial.com/papers/68f74e597f21f73e19e5b2efhttps://doi.org/10.3389/fcvm.2025.1650143
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