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October 21, 2025International Journal of Molecular SciencesOpen Access

Chemical Characterization and In Vitro Antioxidant, Anti-Inflammatory, and Colon Cancer-Preventive Potential of a Polysaccharide Fraction from Macrolepiota procera

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Authors

NNNatalia Nowacka-JechalkeMLMarta Kinga Lemieszek

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Overview

In vitro tests revealed significant antioxidant effects in human colon cancer cells, suggesting polysaccharides may offer health benefits.

Key Points

  • Mp-CPS demonstrates significant antioxidant activity, with higher results in the ORAC test compared to other assays.
  • Chemical analysis shows Mp-CPS primarily consists of glucose- and galactose-based heteropolysaccharides and β-glucans.
  • This research utilized ultrasound-assisted extraction to isolate polysaccharides from edible mushrooms for evaluation.
  • The findings support the potential of Mp-CPS for use in functional foods and nutraceuticals, warranting further exploration.

Cite This Study

Nowacka-Jechalke et al. (2025) studied this question.

synapsesocial.com/papers/68f74e597f21f73e19e5b565https://doi.org/10.3390/ijms26209978
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Characterization of Polysaccharide Extracts of Four Edible Mushrooms and Determination of <i>In</i> <i>Vitro</i> Antioxidant, Enzyme Inhibition and Anticancer Activities2024 · 27 citations
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  3. 3Green synthesis of silver nanoparticles using Macrolepiota procera extract and investigation of their HSP27, HSP70, and HSP90 inhibitory potentials in human cancer cells2022 · 10 citations
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