Abstract Mouse represents a pivotal model and indispensable resource in medical and life sciences, widely used for developmental biology and multi-omics studies. Yet, a comprehensive, integrated mouse multi-omics database remains lacking. Here, we established a mouse multi-omics database, MouseOmics, by integrating 21 genomes distributed among five species within the genus Mus, transcriptomes in 584 tissue samples, proteomes in 285 tissue samples, metabolomes in 143 tissue samples, metallomes in 296 tissue samples, and three variomes covering 52 mouse inbred strains. All mouse multi-omics data can be explored through multiple functional modules with user-friendly web interface. Furthermore, we embedded several useful tools, like MISAweb, for the identification of microsatellite DNAs, and specifically developed the enrichment analysis modules of InterPro, Gene Ontology, and Pathway for mouse. The mouse multi-omics data can be downloaded online conveniently. MouseOmics will be updated regularly with the newly released mouse multi-omics data and can be accessed freely via the address https://www.varnatech.cn/MouseOmics.
Xin et al. (2025) studied this question.