What question did this study set out to answer?

To describe the Mouse Genome Database (MGD) and its role in integrating genetic, genomic, and phenotypic data for the laboratory mouse as a model of human biology and disease.

December 23, 2007Nucleic Acids ResearchOpen Access

The Mouse Genome Database (MGD): mouse biology and model systems

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Authors

CBCarol J. BultJackson Laboratory JEJanan T. EppigJackson Laboratory JKJames A. KadinCentre National de la Recherche Scientifique

Discussion

Member takes

Implication

Database report demonstrates integrated genomic and phenotypic curation in laboratory mice, highlighting enhanced translational research and comparative functional analysis.

Key Points

To describe the Mouse Genome Database (MGD) and its role in integrating genetic, genomic, and phenotypic data for the laboratory mouse as a model of human biology and disease.
Curated data from biomedical literature, individual investigator laboratories, and major public repositories including Ensembl, UniProt, and NCBI.
Standardized data representation using controlled vocabularies and semantic frameworks, including the Gene Ontology (GO) and the Mammalian Phenotype (MP) Ontology.
Developed web-based querying tools and direct computational access pipelines for comparative functional and genomic exploration.
Integrated standardized gene, sequence, variant, and phenotype information to enable translational hypothesis generation across mammalian species.
Incorporated gene trap sequence data linked directly to mouse gene records.
Deployed a customized batch query capability to improve data extraction and high-throughput computational retrieval.

Cite This Study

Bult et al. (2007) studied this question.

synapsesocial.com/papers/6a7e025330df0be8fb5ca32f https://doi.org/10.1093/nar/gkm961

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December 23, 2007Nucleic Acids ResearchOpen Access

The Mouse Genome Database (MGD): mouse biology and model systems

View Full Paper

Ask AI

Bookmark

Authors

CBCarol J. BultJackson Laboratory JEJanan T. EppigJackson Laboratory JKJames A. KadinCentre National de la Recherche Scientifique

Discussion

Member takes

Implication

Database report demonstrates integrated genomic and phenotypic curation in laboratory mice, highlighting enhanced translational research and comparative functional analysis.

Key Points

To describe the Mouse Genome Database (MGD) and its role in integrating genetic, genomic, and phenotypic data for the laboratory mouse as a model of human biology and disease.
Curated data from biomedical literature, individual investigator laboratories, and major public repositories including Ensembl, UniProt, and NCBI.
Standardized data representation using controlled vocabularies and semantic frameworks, including the Gene Ontology (GO) and the Mammalian Phenotype (MP) Ontology.
Developed web-based querying tools and direct computational access pipelines for comparative functional and genomic exploration.
Integrated standardized gene, sequence, variant, and phenotype information to enable translational hypothesis generation across mammalian species.
Incorporated gene trap sequence data linked directly to mouse gene records.
Deployed a customized batch query capability to improve data extraction and high-throughput computational retrieval.

Cite This Study

Bult et al. (2007) studied this question.

synapsesocial.com/papers/6a7e025330df0be8fb5ca32f https://doi.org/10.1093/nar/gkm961

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