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Experiments assess decreased locomotor activity with normothermic blood loss in rats, suggesting hypothermia offers neuroprotection.
In experiments on 55 rats, the effect of body temperature during acute blood loss on the locomotor and exploratory activity of animals on days 3 and 7 of the posthemorrhagic period was assessed. A decrease in exploratory and locomotor activity in animals that had undergone acute blood loss under normothermia was detected. Acute massive blood loss performed under hypothermia does not affect exploratory and locomotor activity, which may indicate neuroprotective mechanisms of natural cooling.
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Tropskaya et al. (2025) studied this question.
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