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November 4, 2025Pediatric Blood & CancerOpen Access

The Association of Sleep Quality, Sociodemographic, and Disease‐Related Factors in Youth Living With Sickle Cell Disease

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Authors

TTTiffany D TuckerDPDakshin PadmanabhanAAAmmar Saadoon Alishlash

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Overview

Retrospective analysis reveals emergency department visits predict sleep disturbances in youth with sickle cell disease, suggesting interventions are needed.

Key Points

  • Emergency department visits for pain increased the odds of sleep disturbances, indicating a crucial risk factor.
  • Higher fetal hemoglobin and less severe SCD genotype were associated with better oxygen saturation and sleep quality.
  • Retrospective clinical database analysis involved polysomnography and logistic regression to evaluate sleep factors.
  • These findings highlight the need for targeted sleep interventions in youth living with sickle cell disease.

Cite This Study

Tucker et al. (2025) studied this question.

synapsesocial.com/papers/690945348f2297dc13533040https://doi.org/10.1002/pbc.32115
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Poor Sleep Quality in Jamaican Adults With Sickle Cell Disease: Prevalence, Risk Factors, and Association With Quality of Life2024 · 3 citations
  2. 2Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study.2026
  3. 3Case–control study of heart rate variability and sleep apnea in childhood sickle cell disease2024
  4. 4Health Related Quality of Life and Psychosocial Profile of Patients with Sickle Cell Disease and Their Caregivers2024
  5. 5Developmental Interconnections in Sickle Cell Disease: A Bio-Psycho-Social Model of Health from Childhood to Young Adulthood2026