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November 8, 2025Cardiology in Review

Effect of Remimazolam on Hemodynamic Stability in Patients Undergoing Cardiac Surgery: A Grade-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials

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Authors

AJAsif JamalSKSuleman KhanMQMaria Qadri

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Overview

Systematic review and meta-analysis reveal remimazolam may enhance recovery but does not improve hemodynamic stability in cardiac surgery.

Key Points

  • Remimazolam did not significantly improve intraoperative hemodynamic stability compared to conventional anesthetics.
  • Pooled analysis showed no significant differences in operative time or mean arterial pressure in 557 patients.
  • Systematic review included seven randomized controlled trials assessing recovery metrics and risk of adverse events.
  • The findings suggest a need for more extensive randomized trials to verify remimazolam's safety and efficacy.

Cite This Study

Jamal et al. (2025) studied this question.

synapsesocial.com/papers/690e8b6ca5b062d7a4e73591https://doi.org/10.1097/crd.0000000000001100
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Remimazolam Versus Propofol for Anesthesia in Intracranial Neurosurgeries: A Systematic Review and Meta-Analysis of Randomized Controlled Trials2026
  2. 2Impact of remimazolam on hemodynamic stability during catheter ablation procedures under general anesthesia2026
  3. 3Remimazolam-based total intravenous vs. sevoflurane-based balanced general anesthesia on perioperative outcomes in adult surgical patients: a systematic review and meta-analysis2026
  4. 4Comparison of Effects of Remimazolam and Midazolam plus Sevoflurane on Intraoperative Hemodynamics and Opioid Administration: A Retrospective Cohort Study2025
  5. 5Remimazolam Versus Propofol for General Anesthesia in Older Adults Undergoing Colon Cancer Surgery: A Systematic Review and Meta-Analysis of Comparative Studies2026