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This review aims to summarize the effects of various exercise modalities on glucose metabolism in older adults.

November 20, 2025Frontiers in PhysiologyOpen Access

Effects of aerobic, resistance, interval, and combined training on glucose metabolism in older adults: insights into type, dose, and mechanism

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This review aims to summarize the effects of various exercise modalities on glucose metabolism in older adults.
Comprehensive search of PubMed and Web of Science databases up to September 2025.
Narrative review of evidence related to exercise modalities.
Focus on aerobic, resistance, high-intensity interval, and combined training.
Combined training shows greater improvements in insulin secretion compared to single-modality interventions.
Highlighted dose-response characteristics of exercise in older adults.
Enhancements in skeletal muscle GLUT4 expression and mitochondrial function are noted.

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Narrative review shows combined training enhances insulin secretion and metabolic markers in older adults, indicating exercise type matters.

Zhang et al. (2025) studied this question.

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Narrative review shows combined training enhances insulin secretion and metabolic markers in older adults, indicating exercise type matters.