Relationship between HbA1c levels and thickness of carotid intima media in prediabetic and diabetic patients

Objective: In this study, it was shown that cardiovascular risk can be reduced by controlling risk factors, and this can be achieved by measuring the carotid intima-media thickness (CIMT) and performing follow-up. An increase in atherosclerosis and cardiovascular risk factors is seen in the prediabetic stage, and CIMT measurement may help in preventing complications before developing diabetes and inflammatory processes. Method: Total 89 patients and 40 healthy controls were analyzed to determine the relationship between their mean HbA1c levels, laboratory data, and CIMT in patients with identified chronic diseases. Results: No significant correlation was noted between the mean HbA1c and right and left CIMT in patients with diabetes mellitus. In the prediabetic patient group, the a weak positive and significant correlation was found between mean HbA1c and bilateral CIMT analysis. Conclusion: In conclusion, the risk of atherosclerosis and cardiovascular complications is increased in the prediabetic stage and non-invasive evaluation with treatment and follow-up may prevent complications, especially cardiovascular ones, in the diabetic stage.