Key result
Higher HbA1c correlates positively with increased carotid intima-media thickness in asymptomatic type 2 diabetes.
Why the study?
The role of carotid intima-media thickening and HbA1c as noninvasive markers for early risk factor assessment in diabetic patients was not well established.
Is there a correlation between HbA1c levels and carotid artery intima-media thickening in diabetic patients?
Cross-Sectional (n=100)
No
Is there a correlation between HbA1c levels and carotid artery intima-media thickening in diabetic patients?
Effect estimate: r = 0.546
p-value: p=<0.001
HbA1c and carotid intima-media thickness may serve as useful non-invasive markers for early risk assessment of progressive atherosclerosis in diabetic patients.
Supports HbA1c and IMT as potential markers in asymptomatic T2D; hypothesis-generating, should not yet change practice.
Introduction: Correlation between carotid artery intima-media thickening and HbA1c levels in diabetic patients as a non invasive marker of progressive atherosclerosis. Objectives: The aim of this study is to study the role of two non invasive markers, carotid intima media thickening and HbA1c in diabetic patients and establish the usefulness of both the parameters in evaluating early risk factor assessment. Material and methods: 100 patients meeting the required criteria were taken coming to OPD/IPD bases to Dhiraj hospital in the age group of 35-70 years.HbA1c levels were used according to American diabetes association. Carotid intima media thickening was measures on B mode ultrasonography in radiology department. Results: among the 100 patients, 68 patients were female and 32 patients were male. The mean of HbA1c values were 8.0 ± 2.2%. The mean cIMT values were 0.78 ± 0.3 cm. Conclusion: HbA1c and carotid artery intimal thickness is useful as a diagnostic marker and early risk factor analysis for atherosclerotic changes in diabetic patients.
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Bhardava et al. (2022) conducted a cross-sectional in Type 2 Diabetes Mellitus (n=100). HbA1c levels was evaluated on Correlation between HbA1c and carotid intima-media thickness (cIMT) (r = 0.546, p=<0.001). HbA1c levels showed a significant positive correlation with carotid intima-media thickness (r = 0.546, p < 0.001) in asymptomatic patients with type 2 diabetes.
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