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November 18, 2025Annals of HematologyOpen Access

Paediatric lymphoblastic lymphoma: a national review of 20 years of clinical and biological data in Ireland

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Authors

ATAmélie TrinquandDBDavid R. BettsSRSean Rooney

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Overview

Retrospective analysis reveals improved outcomes in lymphoblastic lymphoma treatment in children, highlighting risk stratification and genetic profiling needs.

Key Points

  • This review examines clinical and biological features of paediatric lymphoblastic lymphoma in Ireland over two decades.
  • Retrospective review of children with lymphoblastic lymphoma from 2004 to 2023 in Ireland.
  • Cohort analysis included 52 patients with T-LBL and B-LBL subtypes.
  • Data on demographics, clinical presentation, treatment protocols, and outcomes were analyzed.
  • 79% of cases were T-LBL; 21% were B-LBL.
  • 5-year event-free survival was 100% for B-LBL and 85% for T-LBL.
  • Advanced disease presentation in T-LBL included mediastinal masses in 98% of cases.

Cite This Study

Trinquand et al. (2025) studied this question.

synapsesocial.com/papers/6924fef4c0ce034ddc351d8fhttps://doi.org/10.1007/s00277-025-06629-y
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