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December 5, 2025Frontiers in OncologyOpen Access

Comparative prognosis of pediatric lymphoblastic lymphoma: insights from Chinese and international cohorts

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Authors

LZLuyao ZhangChinese Academy of Medical Sciences & Peking Union Medical CollegeYHYongyan HeSun Yat-sen UniversityWLWei LiuZhengzhou Children's Hospital

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Overview

Retrospective analysis reveals survival rates and clinical features of lymphoblastic lymphoma in pediatric patients, implying a need for better risk stratification.

Key Points

  • Overall survival outcomes appear similar between T-LBL and B-LBL, suggesting treatment regimens may require reevaluation.
  • Chi-square test and multivariate Weibull regression were utilized, enabling comprehensive prognostic factor evaluations of pediatric patients.
  • Significant survival differences were noted between treatment periods, indicating potential impacts from disruptions like COVID-19.
  • Clinical features and risk stratification highlight the complexities of pediatric lymphoblastic lymphoma treatment across different cohorts.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/693231118e51979591dcdf2dhttps://doi.org/10.3389/fonc.2025.1626143
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