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November 17, 2025Case Reports in OphthalmologyOpen Access

Recurrent Vision Fluctuations and Orbital Signs Unmasking T-Cell Lymphoma: A Case Report

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Authors

JAJohar AbbasRARabia AsimSASaadullah Ahmad

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Overview

Case report identifies T-cell lymphoma masquerading as Tolosa-Hunt syndrome, suggesting need for prompt histopathological evaluation.

Key Points

  • This report aims to highlight the diagnostic challenges of orbital T-cell lymphoma mistaken for inflammatory conditions.
  • Case report of a young male presenting with unilateral painful ophthalmoplegia.
  • Diagnostic criteria fulfillment for Tolosa-Hunt Syndrome evaluated using ICHD-3.
  • Histopathological evaluation confirmed diagnosis of extranodal orbital T-cell lymphoma.
  • Initial symptoms presented as Tolosa-Hunt Syndrome with steroid responsiveness.
  • Histopathological examination confirmed T-cell lymphoma after symptom recurrence.
  • Timely CHOEP chemotherapy initiation led to slight clinical improvement.

Cite This Study

Abbas et al. (2025) studied this question.

synapsesocial.com/papers/692509fbc0ce034ddc3530e0https://doi.org/10.1159/000549456
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Non-Hodgkin’s Lymphoma Mimicking Orbital Cellulitis: A Diagnostic Dilemma2026
  2. 2Orbital pseudolymphoma: a benign condition mimicking malignancy2024
  3. 3Conjunctival Squamous Cell Carcinoma Masquerading as Orbital Cellulitis in a Patient With Relapsed Mixed Phenotype Acute Leukemia2026
  4. 4Inflammatory disease of the orbit: A case series2024
  5. 5Unmasking an unusual presentation of Hodgkin’s lymphoma masquerading as ocular inflammation: a case report2024 · 1 citations