What question did this study set out to answer?

To explore how maternal stress influences 11β-HSD activity and its implications for pregnancy and fetal health.

November 16, 2025International Journal of Molecular SciencesOpen Access

The Effect of Maternal Stress on 11beta-Hydroxysteroid Dehydrogenase Activity During Pregnancy: Evidence for Potential Pregnancy Complications and Consequences on Fetal Development and Metabolism

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Authors

PPPolina Pavli GMGeorge Mastorakos MEMakarios Eleftheriades

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Implication

Review shows maternal stress correlates with increased pregnancy complications and fetal development risks, indicating potential impact on glucocorticoids.

Key Points

To explore how maternal stress influences 11β-HSD activity and its implications for pregnancy and fetal health.
Review of existing literature on maternal stress and its biological impacts during pregnancy.
Analysis of the role of glucocorticoids in fetal development and metabolism.
Discussion of pathophysiological mechanisms related to placental 11β-HSD activity.
Maternal stress correlates with altered glucocorticoid levels affecting fetal development.
Increased risk of pregnancy complications like preeclampsia and preterm birth associated with maternal stress.
Fetuses may experience intrauterine growth restriction due to maternal stress impacts.

Cite This Study

Pavli et al. (2025) studied this question.

synapsesocial.com/papers/692509ffc0ce034ddc353301 https://doi.org/10.3390/ijms262211071

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Implication

Review shows maternal stress correlates with increased pregnancy complications and fetal development risks, indicating potential impact on glucocorticoids.

The Effect of Maternal Stress on 11beta-Hydroxysteroid Dehydrogenase Activity During Pregnancy: Evidence for Potential Pregnancy Complications and Consequences on Fetal Development and Metabolism

Discussion

Member takes

Implication

Key Points

Cite This Study

The Effect of Maternal Stress on 11beta-Hydroxysteroid Dehydrogenase Activity During Pregnancy: Evidence for Potential Pregnancy Complications and Consequences on Fetal Development and Metabolism

Discussion

Member takes

Implication

Key Points

Cite This Study

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