Case report reveals rhabdomyosarcoma can mimic hematologic malignancies in bone marrow, suggesting diagnostic consideration of immunohistochemical markers.
This case highlights that RMS can initially present with bone marrow metastasis, mimicking hematologic malignancies. When primitive immature cells are observed in bone marrow aspirates, RMS should be considered in the differential diagnosis. A definitive diagnosis relies on a comprehensive approach including immunohistochemical markers, molecular genetic testing, and advanced imaging to identify the primary lesion.
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Xiong et al. (2025) studied this question.
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