Retrospective study shows allergen sensitization profiles can distinguish chronic rhinosinusitis phenotypes, implying different management strategies may be needed.
Key Points
To determine if aeroallergen sensitization profiles differentiate between CRS with nasal polyposis and CRS without nasal polyposis.
Retrospective observational study
241 patients with comorbid CRS and allergic rhinitis
Skin prick testing and in vitro allergy testing were performed
Dermatophagoides pteronyssinus, Alternaria, and animal dander were predictive of CRSwNP
Grass allergen sensitization was also predictive of CRSwNP
Broad sensitization to perennial allergens was not significantly predictive of CRSwNP