What does this research mean for the field?

In surgically treated patients with chronic rhinosinusitis, perennial allergic rhinitis, asthma, and GERD are significantly more prevalent in those with nasal polyps, and the Lund-Mackay CT score is the strongest independent predictor for the presence of polyps. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the prevalence of perennial and seasonal allergic rhinitis among patients undergoing surgery for chronic rhinosinusitis with or without nasal polyps.

September 2, 2026ImmunoOpen Access

Frequency of Allergic Rhinitis Among Phenotypes of Chronic Rhinosinusitis in Patients Treated Surgically: An Experience from a University Hospital

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Authors

ASAleksandra Stajić SZSelena Zečević JSJelena Sotirović

Discussion

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Overview

Retrospective study reveals elevated allergic rhinitis in surgical chronic rhinosinusitis with polyps, indicating strong ties to systemic airway inflammation.

Key Points

To evaluate the prevalence of perennial and seasonal allergic rhinitis among patients undergoing surgery for chronic rhinosinusitis with or without nasal polyps.
Conducted a three-year retrospective single-center study of 155 surgical chronic rhinosinusitis patients without prior sinus operations.
Assessed clinical co-occurrences (allergic rhinitis subtypes, asthma, gastroesophageal reflux disease) alongside peripheral blood eosinophil percentages, total serum IgE, and Lund–Mackay computed tomography scores.
Over 70% of participants had chronic rhinosinusitis with nasal polyps (CRSwNP), which showed higher rates of allergic rhinitis (p = 0.049), perennial allergic rhinitis (p = 0.035), GERD (p = 0.01), and asthma (p = 0.001) compared to cases without polyps.
Strong positive correlations appeared between total IgE and eosinophil percentages (rho = 0.776, p < 0.001) and between eosinophil percentages and Lund–Mackay scores (rho = 0.760, p < 0.001).
Multivariable logistic regression identified the Lund–Mackay score as the sole independent predictor of nasal polyp presence (OR = 1.381, p < 0.001).

Cite This Study

Stajić et al. (2026) studied this question.

synapsesocial.com/papers/6a97e2f6c562ede874ec7673 https://doi.org/10.3390/immuno6030057

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September 2, 2026ImmunoOpen Access

Frequency of Allergic Rhinitis Among Phenotypes of Chronic Rhinosinusitis in Patients Treated Surgically: An Experience from a University Hospital

View Full Paper

Ask AI

Bookmark

Authors

ASAleksandra Stajić SZSelena Zečević JSJelena Sotirović

Discussion

Member takes

Overview

Retrospective study reveals elevated allergic rhinitis in surgical chronic rhinosinusitis with polyps, indicating strong ties to systemic airway inflammation.

Key Points

To evaluate the prevalence of perennial and seasonal allergic rhinitis among patients undergoing surgery for chronic rhinosinusitis with or without nasal polyps.
Conducted a three-year retrospective single-center study of 155 surgical chronic rhinosinusitis patients without prior sinus operations.
Assessed clinical co-occurrences (allergic rhinitis subtypes, asthma, gastroesophageal reflux disease) alongside peripheral blood eosinophil percentages, total serum IgE, and Lund–Mackay computed tomography scores.
Over 70% of participants had chronic rhinosinusitis with nasal polyps (CRSwNP), which showed higher rates of allergic rhinitis (p = 0.049), perennial allergic rhinitis (p = 0.035), GERD (p = 0.01), and asthma (p = 0.001) compared to cases without polyps.
Strong positive correlations appeared between total IgE and eosinophil percentages (rho = 0.776, p < 0.001) and between eosinophil percentages and Lund–Mackay scores (rho = 0.760, p < 0.001).
Multivariable logistic regression identified the Lund–Mackay score as the sole independent predictor of nasal polyp presence (OR = 1.381, p < 0.001).

Cite This Study

Stajić et al. (2026) studied this question.

synapsesocial.com/papers/6a97e2f6c562ede874ec7673 https://doi.org/10.3390/immuno6030057

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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