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To report a rare case of renal cell carcinoma identified through skin metastasis in a dog.

A case of renal cell carcinoma found through skin metastasis in a dog

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Case report reveals adverse prognosis of renal cell carcinoma with skin metastasis in a dog, indicating treatment challenges.

To report a rare case of renal cell carcinoma identified through skin metastasis in a dog.
A French bulldog presented with a skin mass and had an enlarged left kidney discovered during examination.
Surgical removal of the left kidney and skin mass was performed.
Histopathological and immunohistochemical analyses confirmed renal cell carcinoma with a metastatic skin lesion.
The case was atypical, as the renal cell carcinoma was asymptomatic until the skin metastasis appeared.
Post-nephrectomy treatment with toceranib showed less favorable outcomes compared to previous studies.
Skin metastatic lesions may indicate a poor prognosis for dogs with renal cell carcinoma.

Murashima et al. (2025) studied this question.

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