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November 1, 2025Neuro-OncologyOpen Access

INNV-17. Diagnostic Performance and Prognostic Value of the G8 Screening Tool in Older Adults with Newly Diagnosed Glioblastoma, IDH Wild-Type

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Authors

MMMonica Pernia MarinLDLaura DonovanFIFabio Iwamoto

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Overview

Evaluation shows G8 tool predicts one-year mortality in older adults with glioblastoma, indicating improved risk stratification.

Key Points

  • To evaluate the prognostic value of the G8 screening tool in older adults with newly diagnosed glioblastoma.
  • Participants included older adults aged ≥70 years with newly diagnosed glioblastoma, IDH wild-type.
  • G8 screening tool performance was compared with Karnofsky Performance Status and ECOG scores.
  • Data were collected from patients at Columbia University Medical Center.
  • G8 demonstrated prognostic value as an independent predictor of one-year mortality.
  • Identified geriatric impairments significantly associated with treatment outcomes.
  • Risk stratification could be enhanced by validating the G8 tool in this population.

Cite This Study

Marin et al. (2025) studied this question.

synapsesocial.com/papers/6925435ec0ce034ddc358139https://doi.org/10.1093/neuonc/noaf201.0906
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