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November 1, 2025Physics of Fluids

Structural and hemodynamic analysis for predicting side branch occlusion in coronary bifurcation interventions

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Authors

ABAyatollah BayatianANAhmad NooraeenHAHossein Arzani

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Implication

This modeling approach identifies risk factors for side branch occlusion during stenting in atherosclerosis, suggesting improved intervention planning.

Key Points

  • To investigate factors influencing side branch occlusion during main branch stenting in coronary bifurcations.
  • Reconstructed patient-based geometries for simulations of balloon inflation
  • Used computational fluid dynamics to analyze pre-stenting hemodynamic parameters
  • Systematically varied key geometric and pathological factors influencing SBO risk
  • Narrow bifurcation angles and higher stenosis severity increased deformation and disturbed flow
  • Eccentric plaques and larger side branch diameters helped preserve side branch patency
  • Identified hemodynamic parameters could successfully predict SBO risk

Cite This Study

Bayatian et al. (2025) studied this question.

synapsesocial.com/papers/69254371c0ce034ddc35896fhttps://doi.org/10.1063/5.0293854
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Structural and hemodynamic analysis for predicting side branch occlusion in coronary bifurcation interventions2025
  2. 2How bifurcation angle impacts the fate of side branch after main vessel stenting: A retrospective analysis of 1,200 consecutive bifurcation lesions in a single center2015 · 40 citations
  3. 3Risk factors and clinical consequences of side branch occlusion in left anterior descending bifurcation percutaneous coronary intervention: a validation study of the V-RESOLVE score2025 · 2 citations
  4. 4Predictors and Outcomes of Side Branch Occlusion After Main Vessel Stenting in Coronary Bifurcation Lesions2013 · 227 citations
  5. 5Anatomic and Functional Evaluation of Bifurcation Lesions Undergoing Percutaneous Coronary Intervention2010 · 172 citations