Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
January 1, 2025Chinese Journal of Cancer Research

Molecular subtypes and prognostic signature rooted in disulfidptosis highlight tumor microenvironment in lung adenocarcinoma

View Full Paper
Ask AI
Bookmark
Share

Authors

WXWei XiaJLJiwei LiuRCRuo Chen

Discussion

Loading...

Member takes

Overview

This research uncovers a prognostic model using molecular subtypes to enhance survival prediction and therapeutic strategies in lung adenocarcinoma, indicating crucial tumor microenvironment roles.

Key Points

  • To investigate the role of molecular subtypes and disulfidptosis in the tumor microenvironment of lung adenocarcinoma.
  • Analyzed differential expression of DRGs in LUAD
  • Developed a risk model and nomogram for prognosis
  • Examined the impact of tumor microenvironment on therapy response
  • Identified significant prognostic molecular subtypes
  • Developed a nomogram for personalized survival prediction
  • Highlighted the relationship between DRG expression and therapeutic response

Cite This Study

Xia et al. (2025) studied this question.

synapsesocial.com/papers/69255737c0ce034ddc35ae5ehttps://doi.org/10.21147/j.issn.1000-9604.2025.05.11
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Molecular map of disulfidptosis-related genes in lung adenocarcinoma: the perspective toward immune microenvironment and prognosis2024 · 8 citations
  2. 2Disulfidptosis-related lncRNAs signature predicting prognosis and immunotherapy effect in lung adenocarcinoma2024 · 7 citations
  3. 3Therapeutic and prognostic effect of disulfidptosis-related genes in lung adenocarcinoma2024 · 2 citations
  4. 4A novel disulfidptosis-related mRNA signature predicts prognosis and therapeutic response in lung squamous cell carcinoma2025 · 1 citations
  5. 5A disulfidptosis-related lncRNA signature for predicting prognosis and evaluating the tumor immune microenvironment of lung adenocarcinoma2024 · 12 citations