A fluorescent probe for sulfur dioxide reveals intracellular reductive stress triggered by natural antioxidants

Sijie Luo; Lie Xiang; Huihong LIU; Yanyan Luo; Lei Shi; Guhuan Liu; Sheng Yang

doi:10.1039/d5cc05915a

January 1, 2025Chemical Communications

A fluorescent probe for sulfur dioxide reveals intracellular reductive stress triggered by natural antioxidants

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Key Points

Redox homeostasis is altered under conditions of intracellular reductive stress, pointing to the role of sulfur dioxide.
Key evidence includes the development of the DCM-MQE probe for detecting cellular sulfur dioxide more rapidly and sensitively.
Detection focused on the influence of natural antioxidants on sulfur dioxide-induced reductive stress in cells.
The findings highlight the importance of maintaining redox homeostasis, particularly in the context of antioxidant activity.

Implication

Research demonstrates intracellular reductive stress from sulfur dioxide exposure in cells, suggesting natural antioxidants influence redox balance.

Abstract

Sulfur dioxide (SO₂), a pivotal gasotransmitter, is intricately linked to cellular redox homeostasis. Here, we developed the red-emissive DCM-MQE probe for rapid and sensitive detection of intracellular SO₂. Using this...

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Cite This Study

Luo et al. (2025) studied this question.

synapsesocial.com/papers/6928f126a65b730b9ea7a386 https://doi.org/10.1039/d5cc05915a

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A fluorescent probe for sulfur dioxide reveals intracellular reductive stress triggered by natural antioxidants

Key Points

Implication

Abstract

Discussion

Cite This Study

A fluorescent probe for sulfur dioxide reveals intracellular reductive stress triggered by natural antioxidants

Key Points

Implication

Abstract

Discussion

Cite This Study

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