Design, Synthesis and Performance Evaluation of a Fluorescent Probe for the Detection of Sulfur Dioxide In Vitro and Intracellularly

Lin Li; Ning Zhang; Chao Lu; Dan Qiao; Lin-Qing Wang; Linfei Li; Jian-Yong Wang

doi:10.1039/d6ay00623j

January 1, 2026Analytical Methods

Design, Synthesis and Performance Evaluation of a Fluorescent Probe for the Detection of Sulfur Dioxide In Vitro and Intracellularly

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Key Points

This research aims to create a fluorescent probe for detecting sulfur dioxide both in vitro and within cells.
Developed the CouS-CN fluorescent probe using a thiophene-coumarin scaffold.
Evaluated sensitivity and anti-interference performance in detecting sulfur dioxide.
The probe demonstrated high sensitivity for sulfur dioxide detection in vitro.
It showed strong anti-interference capabilities, making it robust in various conditions.

Implication

Experimental work shows a new fluorescent probe detects sulfur dioxide in vitro, indicating promising applications in chemical sensing.

Abstract

In this work, a red-emissive fluorescent probe CouS-CN based on a thiophene-coumarin scaffold was developed for the detection of SO₂. The probe exhibits high sensitivity, broad applicability, strong anti-interference performance,...

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Cite This Study

Li et al. (2026) studied this question.

synapsesocial.com/papers/6a2900566f82f25be989ced5 https://doi.org/10.1039/d6ay00623j

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Design, Synthesis and Performance Evaluation of a Fluorescent Probe for the Detection of Sulfur Dioxide In Vitro and Intracellularly

Key Points

Implication

Abstract

Discussion

Cite This Study

Design, Synthesis and Performance Evaluation of a Fluorescent Probe for the Detection of Sulfur Dioxide In Vitro and Intracellularly

Key Points

Implication

Abstract

Discussion

Cite This Study

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