Observational analysis showed Fuzhenghefuzhiyang Formula alleviated erythema in psoriasis, indicating its pharmacodynamic effect likely involves inflammation and metabolic pathways.
Key Points
Fuzhenghefuzhiyang Formula effectively reduces symptoms like skin thickening and erythema in a psoriasis model.
It regulates multiple biological pathways linked to inflammation and metabolism, identified through network pharmacology.
Employing transcriptome sequencing revealed gene expression changes related to NOD-like receptor signaling pathways.
The study highlights critical connections between metabolomics, inflammation, and purine metabolism in psoriasis management.